Endpoint Protection - Enterprise
Top Microsoft Defender for Endpoint Alternatives and Competitors

ThreatLocker is a global cybersecurity leader that stops cyberattacks before they happen. The company’s Zero Trust Platform prevents breaches from both known and unknown threats by allowing only explicitly trusted software and activity across endpoints, networks, and cloud systems. Built to deploy quickly and scale across complex environments, the platform reduces operational overhead while keeping business running uninterrupted. Headquartered in Orlando, Florida, with offices in Dublin, Dubai, and Brisbane, ThreatLocker protects over 70,000 organizations worldwide.

ThreatDown EDR (endpoint detection and response) is enriched by Malwarebytes global threat intelligence and its patented remediation engine that removes every trace of malware to prevent reinfection. Seven-day ransomware rollback ensures organizations can turn the clock back on attacks and restore systems.

The CrowdStrike Falcon platform leverages real-time indicators of attack, threat intelligence, evolving adversary tradecraft and enriched telemetry from across the enterprise to deliver hyper-accurate detections, automated protection and remediation, elite threat hunting and prioritized observability of vulnerabilities. Purpose-built in the cloud with a single lightweight-agent architecture, the Falcon platform delivers rapid and scalable deployment, superior protection and performance, reduced complexity and immediate time-to-value.

With Acronis Cyber Protect Cloud, you can deliver integrated backup, disaster recovery, cybersecurity, and endpoint management at scale, while preserving your margins and streamlining your business operations with powerful automation capabilities and broad integrations.

Sophos Endpoint powered by Intercept X delivers unparalleled protection, stopping advanced attacks before they impact your systems. Powerful endpoint and extended detection and response (EDR/XDR) tools let your organization hunt for, investigate, and respond to suspicious activity and indicators of an attack.

One intelligent platform for superior visibility and enterprise-wide prevention, detection, and response across your attack surface, from endpoints and servers to mobile devices.

To stay ahead of fast-moving threats, you need AI-powered endpoint security that continuously learns new attack techniques. Cortex XDR™ offers protection that blocks all malware, exploits and fileless attacks to keep your endpoints safe

Secure your endpoints across multiple platforms and locations with detection for known and emerging threats. Equipped with proactive malware defense and engineered to be light on your systems, endpoint security gives you the protection you need with fewer interruptions and false positives.

GravityZone Risk Management reduces the attack surface and measurably improves your security posture, as it identifies, scores and mitigates risks associated with software vulnerabilities, misconfigurations, and user behavior.

OpenText Core Endpoint Protection (Formerly Webroot® Business Endpoint Protection) is a next-generation, fully cloud-based endpoint security solution that harness the power of machine learning to continuously monitor and adapt endpoint threat detection, protection, and prevention.

Trend Micro Apex One™ protection offers advanced automated threat detection and response against an ever-growing variety of threats, including fileless and ransomware. Our cross-generational blend of modern techniques provides highly tuned endpoint protection that maximizes performance and effectiveness.

Arctic Wolf®, the leader in security operations, has acquired Cylance (formerly Blackberry Cybersecurity), a pioneer of AI-based endpoint security. With this acquisition, Arctic Wolf ushers in a new era of simplicity and efficacy to the endpoint security market that will deliver the security outcomes endpoint security customers have been struggling to achieve for years.